[Year : 2005] [Size : 40.2 MB] [Format : PDF] [Pages : 569]
Editor
Gordon M. Cragg
David G.I. Kingston
David J. Newman
ANTICANCER AGENTS from NATURAL PRODUCTS
Line of Contents
Editor
Gordon M. Cragg
David G.I. Kingston
David J. Newman
ANTICANCER AGENTS from NATURAL PRODUCTS
Line of Contents
- Introduction
- Camptothecin and Its Analogs
- The Discovery and Development of the Combretastatins
- Homoharringtonine and Related Compounds
- Podophyllotoxins and Analogs
- Taxol and Its Analogs
- The Vinca Alkaloids
- The Bryostatins
- The Isolation, Characterization, and Development of a Novel Class of Potent Antimitotic Macrocyclic Depsipeptides: The Cryptophycins
- Chemistry and Biology of the Discodermolides, Potent Mitotic Spindle Poisons
- The Dolastatins: Novel Antitumor Agents from Dolabella auricularia
- Ecteinascidin 743 (ET-743; Yondelis™), Aplidin, and Kahalalide F
- Discovery of E7389, a Fully Synthetic Macrocyclic Ketone Analog of Halichondrin B
- HTI-286, A Synthetic Analog of the Antimitotic Natural Product Hemiasterlin
- The Actinomycins
- Anthracyclines
- Ansamitocins (Maytansinoids)
- Benzoquinone Ansamycins
- Bleomycin Group Antitumor Agents
- Biochemical and Biological Evaluation of (+)-CC-1065 Analogs and Conjugates with Polyamides
- Epothilone, a Myxobacterial Metabolite with Promising Antitumor Activity
- Enediynes
- The Mitomycins
- Staurosporines and Structurally Related Indolocarbazoles as Antitumor Agents
- Combinatorial Biosynthesis of Anticancer Natural Products
- Developments and Future Trends in Anticancer Natural Products Drug Discovery
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